you should not use the Eqyss product with Betadine, there are warnings on the bottles...if you are using Eqyss use both the Eqyss medicated shampoo and the spray or gel.  They are expensive but work very well.  Keep your horse dry and exposed to the sun and air as much as possible.  If you are blanketing wash and completely dry the blankets frequently to avoid the fungus spreading.

 I have used both concurrently with success.I just don't use them at the same time.I use the Equyss product in between shampoos or in the wintertime when I can't bathe horses.The label on the Micro-Tek does sayNOT to use with iodine based shampoos.I have done so,but as I say,between shampoos,when my horse has gotten healed from the worst of the condition,and in winter when unable to bathe one.

I have used a solution of 50% rubbing alcohol and 50% white vinegar with great success on rain rot.  Everyone that I have told about this solution has had good results as well.  Just pour it on the affected area or put it in your hand and rub it on.  It sounds harsh but it works and it did not seem to bother my horses when I was applying it.

Ride ON!

Thanks, everyone for the info. Appreciate all the replies. Will try one of these for sure.

I have not seen Eqss stuff but I use pure betadine on my horse's rain rot each spring and fall. Just rub it in with my hand.The rain rot is gone in a couple days with no problems for my horse. There is a vet college only a few miles from me and they recommended the betadine.

Keep a gallon of Iodine shampoo in your tack area and you'll always be prepared.

Cleaning brushes and blankets routinely will also help to stop or slow the spread of nasty infections.

Adding regular povidone iodine to any shampoo works in a pinch!

Shapley's M-T-G is also a very good product. It helps the scabs to loosen and come off. I have heard if you pull these scabs off, it can be painful to the horse. You have to really shake the bottle up before you apply it and it doesn't smell real good, but it does the job.